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br Materials and Methods br Results br Discussion Voluminous
2024-04-15
Materials and Methods Results Discussion Voluminous literature is available describing the regulation of tachykinins homeostasis by central and peripheral mechanisms in poultry [35,36]. However, the neuroendocrine mechanism(s) of photoperiod induced hypothalamic regulation of food intake an
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In young animals the HT A receptor
2024-04-15
In young animals, the 5-HT2A protein phosphatase inhibitor antagonist ketanserin, at relatively low concentrations, shifted 5-HT concentration-response curves rightward, suggesting a role for 5-HT2A receptors in mediating 5-HT-induced contractions of the ureter. The slopes of the ketanserin Schild
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In addition to pH regulation by
2024-04-15
In addition to pH regulation by ion (counter-) fluxes, acidification is regulated by the abundance of V-ATPase on organelles, by the pumping activity of the complex and by proton leakage. In yeast, the V-ATPase VO subunit a is the only subunit expressed in two isoforms termed Stv1p and Vph1p. V-ATPa
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ATM is generally regarded to be the principal mediator
2024-04-15
ATM is generally regarded to be the principal mediator of the G1 DMPO checkpoint, whereas the induction of the intra-S-phase and G2/M checkpoints are usually primarily related to ATR function. However, several studies have demonstrated that, depending on the cellular context and type of DNA damage,
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The objectives of this study were
2024-04-15
The objectives of this study were to investigate 1) the mRNA and protein expression of apelin and APJ in porcine ovarian follicles of different sizes, and their immunolocalization and concentrations in follicular fluid and ovarian follicle, and 2) the direct effect of recombinant human apelin-13 on
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The putative residue apelin proprotein
2024-04-15
The putative 55-residue apelin proprotein (proapelin or apelin-55) is processed from a 77-residue preproprotein through removal of a 22-residue signal peptide (Table 1). Apelin-55 is further processed into bioactive isoforms of 36, 17, or 13 residues, likely through protease-mediated mechanisms. To
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In addition understanding the relationship between
2024-04-15
In addition, understanding the relationship between human metabolic processes and dietary antioxidant intake would provide opportunities for altering the diet to improve health (Prior, 2015). Prior et al. (2007) emphasized that excess reactive oxygen species, which occurred during the metabolism of
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Serum concentrations of acute phase proteins
2024-04-15
Serum concentrations of acute phase proteins (APP) and of antioxidants have proved to be clinically useful biomarkers of pyometra in different species, including bitches, cows and mares [[11], [12], [13], [14], [15]]. Acute phase proteins are being increasingly used in both human and veterinary medi
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br Materials and methods br Results and discussion
2024-04-15
Materials and methods Results and discussion Conclusions Acknowledgements Introduction Infections in children aged 0–21 years who reside in long-term care (LTC) facilities are common due to underlying complex medical conditions, use of invasive devices such as urinary catheters and ve
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br Results and discussion In order
2024-04-15
Results and discussion In order to investigate the assembly dynamics and aggregate structures of Aβ16-22, twelve molecular systems with the number of peptides varying from 1 to 12 were studied. In all simulations, the same peptide concentration (~15 mM) was maintained by adjusting the dimensions
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br The lipoxygenase pathway in diseases of the nervous
2024-04-13
The 12/15-lipoxygenase pathway in diseases of the nervous system Conclusions and future perspectives Arachidonic ITE and other polyunsaturated fatty acids, and their lipid metabolites, play very important roles in human health and disease. This review has outlined the functions of 12- and 15-l
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br Discussion Here we show opposing effects of
2024-04-13
Discussion Here, we show opposing effects of iontophoretically administered phenylephrine,aselective α1-AR agonist, on firing of putatively DAergic and non-DAergic neurons recorded in vivo in the VTA of urethane anaesthetized rats. Phenylephrine application caused a relatively weak decrease in fi
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br Results and discussion The classical radiochemical
2024-04-13
Results and discussion The classical radiochemical adenosine kinase assays developed to monitor AdK activity utilize [3H]adenosine or [14C]adenosine, respectively. The assays are terminated by spotting the incubation mixture onto diethylaminoethyl (DEAE) anion exchange filter disks or onto a poly
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The myasthenia scale of Millichap
2024-04-13
The myasthenia scale of Millichap and Dodge was used in our study for ease of comparison of our retrospective data with previous paediatric studies. Our results, with 30% achieving complete remission and 95% achieving at least some degree of clinical improvement following thymectomy, are comparable
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To date the modes of actions of pharmaceuticals in humans
2024-04-13
To date, the modes of actions of pharmaceuticals in humans and mammals are well-known (Fent et al., 2006), whereas knowledge of aquatic organisms, particularly invertebrates, is limited. This is problematic as these contaminants/pollutants have potentially harmful effects on wildlife organisms that
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